Meatloaf Grilled Cheese – A Comfort Food Mashup You’ll Love

When two comfort food classics collide, you get the ultimate sandwich: Meatloaf Grilled Cheese. Thick slices of savory meatloaf are layered with gooey melted cheese and grilled between buttery, golden bread for a meal that’s hearty, nostalgic, and downright irresistible. This recipe is perfect for using up leftover meatloaf and turning it into a whole new dish that feels just as special as the first time around.

Why You’ll Love This Recipe

Comfort Food Fusion: Combines the best of meatloaf and grilled cheese.
Perfect for Leftovers: A clever and delicious way to repurpose last night’s dinner.
Cheesy Goodness: Melty, gooey cheese holds everything together.
Quick & Easy: Ready in under 20 minutes.

Ingredients

• 4 slices hearty bread (sourdough or sandwich bread works well)
• 4 slices leftover meatloaf (about ½-inch thick)
• 4 slices cheddar or mozzarella cheese (or a mix)
• 2 tbsp butter, softened
• Optional add-ons: caramelized onions, pickles, or a drizzle of ketchup or BBQ sauce

Instructions

1. Prepare the Bread
Spread softened butter on one side of each slice of bread.

2. Layer the Sandwiches
On the unbuttered side of two slices, place one slice of cheese, 2 slices of meatloaf, and another slice of cheese. Top with the remaining bread, buttered side facing out.

3. Grill the Sandwiches
Heat a skillet or griddle over medium heat. Place sandwiches in the pan and cook for 3–4 minutes per side, pressing gently with a spatula, until the bread is golden brown and the cheese is melted.

4. Serve
Slice in half and serve hot with ketchup, BBQ sauce, or your favorite dipping sauce.

Nutritional Information

Calories: 420
Carbohydrates: 28g
Fat: 20g
Protein: 27g
Fiber: 2g

Tips for Success

• Use Sturdy Bread: Thick-cut bread helps hold the filling without getting soggy.
• Low & Slow Heat: Prevents burning the bread before the cheese melts.
• Extra Flavor Boost: Try sharp cheddar, smoked gouda, or pepper jack for variety.
• Upgrade It: Add caramelized onions or a little BBQ sauce inside for a flavor twist.

Why This Recipe Works

The rich, savory flavor of meatloaf pairs beautifully with melted cheese and crispy bread, creating the ultimate sandwich. It’s quick, satisfying, and a smart way to reinvent leftovers into a new comfort food classic.

Meatloaf Grilled Cheese is a genius mashup that combines two timeless favorites into one unforgettable sandwich. With its golden, buttery crust, melty cheese, and hearty meatloaf filling, it’s the perfect comfort food for lunch, dinner, or even a late-night craving. Once you try it, this will become your new favorite way to enjoy leftover meatloaf.