Craving the flavors of a juicy cheeseburger and a slice of pizza all in one dish? This hearty, cheesy, oven-baked casserole brings those two favorites together in a satisfying, lighter version that’s perfect for weeknight dinners or weekend indulgence—without going overboard.
Why You’ll Love This Recipe
Two Comfort Foods in One: Combines everything you love about burgers and pizza.
Family-Friendly Favorite: Great for picky eaters and easy to portion.
Satisfying Yet Balanced: Uses lean meat and lighter cheese while still delivering rich flavor.
Great for Meal Prep: Reheats beautifully for lunches or quick weeknight leftovers.
Ingredients
- 1 lb lean ground turkey or extra-lean ground beef
- 1 small onion, diced
- 1/2 tsp garlic powder
- 1 tsp Italian seasoning
- 1/2 cup pizza sauce (low-sugar or no added sugar)
- 1/2 cup canned diced tomatoes, drained
- 3/4 cup reduced-fat shredded mozzarella cheese
- 1/2 cup shredded reduced-fat cheddar cheese
- 1/4 cup turkey pepperoni slices (optional)
- 3 low-carb or whole grain sandwich thins or light buns, torn into pieces
- Cooking spray
- Salt and black pepper to taste
- Fresh parsley or basil for garnish (optional)
Instructions
Cook the Meat
- Preheat oven to 375°F (190°C).
- In a skillet over medium heat, spray with cooking spray and sauté diced onion until soft.
- Add ground turkey or beef, garlic powder, Italian seasoning, salt, and pepper. Cook until browned and fully cooked.
- Stir in pizza sauce and diced tomatoes. Simmer for 3–4 minutes, then remove from heat.
Assemble the Casserole
- Lightly coat a 9×9 inch baking dish with cooking spray.
- Spread torn sandwich thins/bun pieces on the bottom.
- Layer meat mixture evenly on top.
- Sprinkle both cheeses over the meat. Add pepperoni slices, if using.
Bake
- Bake uncovered for 20–25 minutes, until the cheese is melted and bubbly.
- Let rest 5 minutes before serving. Top with fresh herbs if desired.

Nutritional Information (Per Serving, Approximate)
Calories: 280 | Protein: 28g | Carbs: 12g | Fat: 13g | Fiber: 3g | Sugar: 4g
Tips for Success
- Choose Lean Meat: Helps cut down fat while keeping protein high.
- Use Sandwich Thins: A lighter base that mimics pizza crust without the extra calories.
- Customize the Toppings: Add mushrooms, bell peppers, or olives to suit your taste.
- Double the Batch: Freeze one for later—just reheat in the oven for a quick meal.
Why This Recipe Works
- Bold Flavor, Balanced Nutrition: Classic pizza and burger taste with better-for-you ingredients.
- Comfort Food Made Smarter: You won’t miss the fast food when this hits your table.
- Layered for Satisfaction: The soft bread base, saucy meat layer, and melty cheese create the perfect bite.
The Ultimate Cheesy Pizza Burger Bake is everything you want in a comfort meal—cheesy, hearty, and packed with flavor—while still fitting into a more mindful eating plan. Serve it with a side salad or roasted veggies and dig into this crave-worthy classic remix.
Ultimate Cheesy Pizza Burger Bake – The Best of Both Worlds
6
servings15
minutes30
minutes280
kcal45
minutesCraving the flavors of a juicy cheeseburger and a slice of pizza all in one dish? This hearty, cheesy, oven-baked casserole brings those two favorites together in a satisfying, lighter version that’s perfect for weeknight dinners or weekend indulgence—without going overboard.
Ingredients
1 lb lean ground turkey or extra-lean ground beef
1 small onion, diced
1/2 tsp garlic powder
1 tsp Italian seasoning
1/2 cup pizza sauce (low-sugar or no added sugar)
1/2 cup canned diced tomatoes, drained
3/4 cup reduced-fat shredded mozzarella cheese
1/2 cup shredded reduced-fat cheddar cheese
1/4 cup turkey pepperoni slices (optional)
3 low-carb or whole grain sandwich thins or light buns, torn into pieces
Cooking spray
Salt and black pepper to taste
Fresh parsley or basil for garnish (optional)
Instructions
- Cook the Meat
Preheat oven to 375°F (190°C).
In a skillet over medium heat, spray with cooking spray and sauté diced onion until soft.
Add ground turkey or beef, garlic powder, Italian seasoning, salt, and pepper. Cook until browned and fully cooked.
Stir in pizza sauce and diced tomatoes. Simmer for 3–4 minutes, then remove from heat. - Assemble the Casserole
Lightly coat a 9×9 inch baking dish with cooking spray.
Spread torn sandwich thins/bun pieces on the bottom.
Layer meat mixture evenly on top.
Sprinkle both cheeses over the meat. Add pepperoni slices, if using. - Bake
Bake uncovered for 20–25 minutes, until the cheese is melted and bubbly.
Let rest 5 minutes before serving. Top with fresh herbs if desired.
Notes
- Choose Lean Meat: Helps cut down fat while keeping protein high.
Use Sandwich Thins: A lighter base that mimics pizza crust without the extra calories.
Customize the Toppings: Add mushrooms, bell peppers, or olives to suit your taste.
Double the Batch: Freeze one for later—just reheat in the oven for a quick meal.